SEDATIVES USED IN SURGERY – BEST CHOICES FOR ANESTHESIA

two. Histamine Receptor Antagonism: Some sedatives, such as antihistamines, exert their sedative effects by blocking histamine receptors inside the brain, especially H1 receptors. Histamine plays a role in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness.Ample and well-managed reports have failed to exhibit a danger